Picolax is a strong laxative that will cause diarrhoea and empty the bowel. It is wise to stay within easy reach of a toilet once you have taken this medication. Avoid travelling or going to work.As directed I took my first sachet of Picolax at 8am this morning. It tasted vaguely orangey. At 8.45am I needed to empty my bag. I guess the laxative is working then. I haven’t eaten anything for about 12 hours now. Instead of my usual 4 Weetabix I’m having a black coffee for breakfast. No milk allowed. I'm not going into work today. And I won't be straying too far from my computer. Or the bathroom. It’s going to be a long day.